By M. Rossanda (auth.), P. E. Maspes, B. Hughes (eds.)
Hypothermia used to be first utilized to the human in 1940 via Smith and Fay in an try to have an effect on the expansion of malignant tumours, and located its most crucial program to start with in open cardiac surgical procedure and latterly in neurosurgery. the 1st effects in regards to the use of hypothermia in neurosurgery have been suggested on the First Inter nationwide Congress of Neurological Sciences held in Brussels in 1957. a similar topic used to be back thought of on the annual assembly of the Societe de Neurochirurgie de Langue Franl}aise held in Montpellier in'1962. whilst i used to be charged with the duty of organizing the Symposium on the moment eu Congress of Neurosurgery, i presumed it advert visable to place ahead back the matter of using hypothermia in neurosurgery. although this approach had swiftly develop into well known and a mass of courses from an important neurosurgical centres of the area had seemed, many difficulties remained un solved, and particularly these on the topic of the alternative of circumstances to be handled, the usefulness of the technique and its attainable dangers.
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Additional info for Hypothermia in Neurosurgery: Symposium Organized by P. E. Maspes at the Second European Congress of Neurosurgery Rome, April 18–20, 1963
Norris, K. D. Hall, and O. Ajmone-Marsan: The electrographic activity of the cooled human frontal lobe and its response to hypotension. J. Neurosurg. 17 (1960), 905-922. - Oate, J. ten, G. P. M. Horsten, and L. J. Koopman: The influence of the body temperature on the EEG of the rat. EEG Clio. NeurophysioI. 1 (1949), 231-235. Oazzullo, O. : Sistema nervoso e ibernazione artificiale. Rassegna critica e contributo di neurofisiopatologia sperimentale. Riv. Spero Freniat. 80 (1956), 3-101. , and D. Bonnet: Cortical excitability and induced hypothermia.
Sie betonen die praktische Bedeutung der folgenden Beobachtungen: a) Bis 30 -3P C Korpertemperatur ist das BewuBtsein erhalten. ) bilateral symmetrisch ausgepragt. c) Die Pupillenreaktion auf Licht wird in Hypothermie verlangsamt; die Pupillenreaktion kann so langsam werden, daB sie zu fehlen scheint. d) Eine schon vorher vorhandene neurologische Symptomatik bleibt wahrend und nach maBiger Hypothermie unverandert. Es muB aUerdings betont werden, daB es bei Patienten in Hypothermie schwieriger ist, die neu· rologischen Symptome nachzuweisen als in N ormothermie.
In 7 out of 25 control patients (20 had aneurysms) these influences could be nevertheless reduced to a minimum. Thus, controls carried out during gradual temperature falls revealed a progressive and constant (although not marked) prolongation of the dextran tolerance test values in Changes in the Blood Clotting Mechanism 53 association with a slight prothrombin hypoactivity. This finding was found in 6 of the 7 cases (Figs. 1 and 2). T. P. 8 De' tBe~mmn~pmOqff317$&&Q17 Fig. 2 values markedly shorter than basal levels.