Nanotechnology in Drug Delivery by Daniel P. Otto, Melgardt M. de Villiers (auth.), Melgardt M.

By Daniel P. Otto, Melgardt M. de Villiers (auth.), Melgardt M. de Villiers, Pornanong Aramwit, Glen S. Kwon (eds.)

The reader might be brought to varied points of the basics of nanotechnology dependent drug supply platforms and the appliance of those structures for the supply of small molecules, proteins, peptides, oligonucleotides and genes. How those structures conquer demanding situations provided by way of organic limitations to drug absorption and drug focusing on may also be described.

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We now focus again on the potential effect of a polymer matrix as a medium for confining the crystallization of organic crystals. Upon achieving a critical size, crystal nuclei will become stable resulting in the growth of mature crystals. The sum of the surface free energy (dominating the precritical size stage) and volume free energy (dominating the stage beyond the critical nucleus size) determines this growth process. Structures that mimic the crystal packing of mature crystal forms could be exploited to manipulate polymorphism, crystal habit and size (Oxtoby, 1998).

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