New Developments in Biosciences: Their Implications for by R. J. Samsom (auth.), Anton C. Beynen, Henk A. Solleveld

By R. J. Samsom (auth.), Anton C. Beynen, Henk A. Solleveld (eds.)

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Extra info for New Developments in Biosciences: Their Implications for Laboratory Animal Science: Proceedings of the Third Symposium of the Federation of European Laboratory Animal Science Associations, held in Amsterdam, The Netherlands, 1–5 June 1987

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Thus, in nude mice the severe cell dependent resistance mice may be more resistant to deficiency in T- may result in a more dramatic change in the ultimate control of infection with Listeria monocytogenes than in nude rats. As in true for resistance to the bacterial infection with Listeria monocytogenes, also the resistance to the infection with the parasite Trichinella spiralis is littermates different in nude rats compares to +/rnu (40). Nude rats are unable to mount IgM, IgG and IgE-class antibodies against T.

Fortunately, they did not join the Animal Rightists, but sought co-operation with the scientists. Now the Association has members in various parts of Finland, professors as well as laboratory animal technicians, students and laymen. The Association has organized seminars and symposia on refined techniques and handling of laboratory animals. The good relations between animal welfarists and laboratory animal technicians is expressed by the fact that the Association has financially supported the preparation of the Finnish Association of Laboratory Animal Technicians Slide Series on modern laboratory animal techniques.

Germinal centers are only incidentally nude rat, while seen in the they were not observed in the nude mouse (6). In the spleen of nude rats the reticular framework around the central artery was virtually free of lymphocytes. The morphology of the pituitary gland, thyroid, adrenals, ovaries, and testes in nude rats did not differ from that in their heterozygous littermates. In contrast, changes do occur in the endocrine the in organs of nude mouse (8-11). For example, Pierpaoli and Sorkin (8) observed the pituitary endoplastic gland reticulum in that granules were absent and that somatotropin producing cells of l2-week old nude mice was enlarged, whereas Ruitenberg and Berkvens (10) found a decrease in size and number of acidophilic (presumably STH) cells in 8and 12-week old male nude mice.

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