Nucleic Acid Nanotechnology by Lei Liu, Flemming Besenbacher, MingDong Dong (auth.), Jørgen

By Lei Liu, Flemming Besenbacher, MingDong Dong (auth.), Jørgen Kjems, Elena Ferapontova, Kurt V. Gothelf (eds.)

This quantity on nucleic acid nanotechnology deals authoritative, updated and entire insurance of nanotechnological reviews and functions of nucleic acids. It offers reports of varied elements of nucleic acid nanotechnology, each one written by way of an the world over prime professional within the box, and offers state of the art and up to date advances in nucleic acid artificial transformations, nanoscale layout, manipulation and present and destiny purposes in bioengineering, medication, electronics, genetic research, chemistry, molecular biology, floor and fabric sciences. It examines how nucleic acid examine is merging with nanotechnology, permitting the nanoscale homes of nucleic acid to be exploited in acting not easy nanotechnological initiatives, from nanorobotics and nanosensing to nucleic acid computing. This booklet will certainly gain an individual who's drawn to nanotechnological suggestions of nucleic acid layout and functions, and gives a priceless source for instructing those thoughts. it's crucial interpreting for a wide viewers of scientists either in academia and who desire to extend their services at the strength of nucleic acid capabilities and applications.

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Extra resources for Nucleic Acid Nanotechnology

Sample text

2 Commonly Used Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Optical Tweezers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Magnetic Tweezers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Nanopore Force Spectroscopy . . . . . .

4 Expanded Kinetic Theory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Nonequilibrium Thermodynamics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Work Measurement in Practice . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Intermediate States in the Energy Landscape . . . . . . . . . . . . . . . . . . .

Single-molecule force spectroscopy has been realized only within the last decades, and its success is crucially connected to the technological development that has allowed single-molecule resolution. This chapter provides an introduction to in vitro force spectroscopy of individual DNA and RNA molecules including the most commonly used techniques, the theory and methodology necessary for understanding the data, and the exciting results achieved. Three commonly used single-molecule methods are emphasized: optical tweezers, magnetic tweezers, and nanopore force spectroscopy.

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